By Reginald H. Garrett, Charles M. Grisham

Carrying on with Garrett and Grisham's leading edge conceptual and organizing framework, "Essential Questions," BIOCHEMISTRY courses scholars via direction options in a manner that finds the wonder and value of biochemistry within the daily world.The book's balanced presentation has been streamlined for elevated readability and readability--and to make it extra attention-grabbing to visible inexperienced persons, this variation additionally contains new pictures and illustrations that express the subject material continuously during the textual content. New end-of-chapter difficulties, MCAT perform questions, and the remarkable text/media integration with the facility of CengageNOW around out this remarkable package deal, giving scholars the instruments they should grasp path recommendations and increase serious problem-solving abilities they could draw upon lengthy after the direction ends.

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Extra info for Biochemistry (4th Edition)

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1 (a) Gelada (Theropithecus gelada), a baboon native to the Ethiopian highlands. (b) Tropical orchid (Bulbophyllum blumei), New Guinea. This icon, appearing throughout the book, indicates an opportunity to explore interactive tutorials and animations and test your knowledge for a quiz or an exam. com/login 2 Chapter 1 The Facts of Life: Chemistry Is the Logic of Biological Phenomena Entropy is a thermodynamic term used to designate that amount of energy in a system that is unavailable to do work.

Chapter 26 The phenomenon of metabolic channeling as a principle in metabolic organization and integration is emphasized. Chapter 27 The role of AMP-activated protein kinase as the sensor of cellular energy levels and regulator of whole-body energy homeostasis is introduced, and the biochemical connections between caloric restriction or red wine consumption to prolonged lifespan are explored. Chapter 29 The structural studies of RNA polymerase that brought Roger Kornberg the Nobel Prize form the basis for a deeper understanding of transcription.

The structure of DNA multiplexes composed of 3 or 4 polynucleotide strands and the higher orders of structure in RNA molecules are new topics in this chapter. Chapter 12 The use of RNA interference (RNAi) as a tool to discover gene function and various analytical methods for probing protein-protein interaction are two new methodologies pertinent to this chapter. xxix xxx Preface Chapter 13 The possibility of creating enzymes designed to catalyze any desired reaction is introduced. Chapter 14 Enzyme mechanisms (Chapter 14 Mechanisms of Enzyme Action) are presented before enzyme regulation (Chapter 15 Enzyme Regulation), allowing students to appreciate the catalytic power of enzymes immediately after learning about their kinetic properties (Chapter 13 Enzymes—Kinetics and Specificity).

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