By Nicholas P. Money (auth.), Professor Dr. Richard J. Howard, Professor Dr. Neil A. R. Gow (eds.)

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1998; Barral et al. 1999). The delay is mediated through the function of the tyrosine kinase Swe1, the S. pombe Wee1 homologue (Russell and Nurse 1987a), and through the delayed accumulation of the G2 cyclins, Clb1 and Clb2 (Booher et al. 1993; Lew and Reed 1995b; McMillan et al. 1998; Barral et al. 1999). Swe1 inhibits the CDK by specifically phosphorylating its tyrosine 19 residue (Sia et al. 1996), and by an as-yet-unclear mechanism, which does not require the Swe1 kinase activity (McMillan et al.

Structural Components Important for Cell Shape and Polarity. . . . . . . . A. The Actin Cytoskeleton ................. B. Septins ................................ C. The Cell Wall . . . . . . . . . . . . . . IV. Polarized Secretion ..................... V. Regulation of Structural Components ..... A. Establishment of Polarized Growth Site .... B. Components That Ensure the Quality of Polarized Growth. . . . . . . . . . . C. Rho-Type Guanosine Triphosphatases (GTPases) .............................

IV. Polarized Secretion ..................... V. Regulation of Structural Components ..... A. Establishment of Polarized Growth Site .... B. Components That Ensure the Quality of Polarized Growth. . . . . . . . . . . C. Rho-Type Guanosine Triphosphatases (GTPases) ............................. D. p21-Activated Kinases (PAKs) ............ 1. Ste20 ............................... 2 Cb4 ................................ E. Mitogen-Activated Protein (MAP) Kinase Pathways. . . . . . .

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